Cheers,
This has been really annoying me since I got this PC last weekend
(MS help no good :-)
Thank you! Thought I had worn out the F2 key 
you just saved my day !!! have been swearing my head off for the last hour or so...........
This advice may be 9 years old, but it has solved the issue for me - thank you!
Cool advise , helped me solve the problem. Thanks.
9 years after you first posted, this thread still helping us figure things out.
Thanks for the info missb
Thanks! It worked! I though there was some Excel update that broke something but this was it. Thanks again!
Thank you!!!!
Same think happened to me.
Thank you for the tip.
I have a Logitech wireless and simply hit the F mode key and it fixed the problem so F2 works for edits again.

Sooo simple! Yet I had searched 10 other links and did not find a solution until now.
Thanks!